Isisdoris Rodrigues

Postdoc

Isisdoris is a biologist who graduated from the Federal University of Acre, Brazil. Her scientific focus is on alternative methods to animal testing. She earned a master’s degree in 2018 and a doctorate in 2022 in Genetics from the Federal University of Paraná, Brazil, where she worked in the In Vitro (Eco) Toxicology Laboratory. During her master’s studies, she developed 3D spheroidal liver models to test the genotoxicity of substances.
Her doctoral research focused on investigating the skin immunotoxic effects of endocrine disruptors, employing various models, including reconstructed human epidermis (RHE), 2D keratinocyte cultures, and THP-1 cells. She combined these with in silico tools to evaluate new approach methodologies for predicting skin sensitization, genotoxicity, mutagenicity, and carcinogenicity. Part of this work was conducted at the University of Milan, Italy, in the Laboratory of Toxicology.
At the end of 2022, she began a postdoctoral position in the Laboratory of Basic Biology Stem Cells at the Oswaldo Cruz Foundation (FIOCRUZ) in Paraná, Brazil. There, she has been developing a microfluidic system for drug toxicity screening using image analysis and testing a cost-effective pump for microfluidic applications in Brazil. Additionally, she has worked on designing layout methods using Harmony Software for chip analysis with Operetta (Perkin-Elmer).
During this period, she was selected and has studied high content Screening analysis in Institut Pasteur Korea (Seoul, South Korea) in 2023 and won the Brazilian award from FIOCRUZ, for best postdoctoral research for “Biological Sciences applied to Health and Biomedicine” in 2024.
Since November 2024, she has been a part of the MicroOrganoLab team, working on the development of an innervated white adipose-on-a-chip model for diabetes research.
In her free time, she enjoys dancing, listening to music, traveling, playing group sports, and spending time in nature.